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Query: RAD18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAD18 2 6.624 0.290 -0.170
RAD18 2 6.624 0.290 -0.170 -0.119
RAD18 2 6.624 0.290 -0.170 0.133 -0.034 0.651

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAD18 Ubiquitylation K333 0.989 1.516 _DQTEK(gl)EIDEIHSK_
RAD18 Phosphorylation S103 1.453 1.119 _NHLLQFALESPAKS(ph)PASSSSK_
RAD18 Ubiquitylation K154 0.097 0.713 _EMSGSTSELLIKENK(gl)SK_
RAD18 Ubiquitylation K151 0.809 0.351 _EMSGSTSELLIK(gl)ENK_
RAD18 Phosphorylation S471 0.270 0.272 _NDLQDTEIS(ph)PR_
RAD18 Ubiquitylation K156 0.757 0.161 _SK(gl)FSPQK_
RAD18 Phosphorylation S99 -0.633 0.106 _NHLLQFALES(ph)PAK_
RAD18 Ubiquitylation K261 0.601 0.053 _LK(gl)EHGLSIQGNK_
RAD18 Ubiquitylation K115 -0.231 -0.368 _NLAVK(gl)VYTPVASR_
RAD18 Ubiquitylation K161 -0.335 -0.403 _FSPQK(gl)EASPAAK_
RAD18 Ubiquitylation K110 -0.405 -0.669 _SPASSSSK(gl)NLAVK_
RAD18 Ubiquitylation K110 -0.405 -0.669 _SPASSSSK(gl)NLAVK_
RAD18 Ubiquitylation K370 -0.695 _IAGMSQK(gl)TVTITK_
RAD18 Ubiquitylation K258 -0.742 _TVYNLLSDRDLKK(gl)_
RAD18 Ubiquitylation K13 0.971 -0.795 _TVTITK(gl)EDESTEK_
RAD18 Ubiquitylation K376 0.971 -0.795 _TVTITK(gl)EDESTEK_
RAD18 Ubiquitylation K73 -1.744 _TQCPTCCVTVTEPDLK(gl)NNR_
RAD18 Ubiquitylation K186 -1.903 -2.009 _SVEEIAPDPSEAK(gl)RPEPPSTSTLK_
RAD18 Ubiquitylation K197 -1.182 _RPEPPSTSTLK(gl)QVTK_
RAD18 Ubiquitylation K309 0.251 _SAAEIVQEIENIEK(gl)TR_
RAD18 Ubiquitylation K318 1.786 _LEASK(gl)LNESVMVFTK_

Background Information for RAD18:


Pubmed-RAD18 »
Uniprot-RAD18 »
Biogrid-RAD18 »
ProteomicsDB-RAD18 »

Tumorportal-RAD18 »
COSMIC-RAD18 »
GenomeRNAi-RAD18 »
Genecards-RAD18


Protein-protein Interactions for RAD18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CERK Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM178A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD18 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2A Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BATF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IRF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRP9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEANC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF501 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF692 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAD18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SAP_dom IPR003034 1.96
Category members Znf_RING IPR001841 0
Category members Znf_Rad18_put IPR006642 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RAD18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAD18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0003684 damaged DNA binding Database 4.54
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005657 replication fork Database 0.95
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0009411 response to UV Database 0.79
Category members GO Category GO:0001741 XY body Database 0.47
Category members GO Category GO:0031593 polyubiquitin binding Database 0.38
Category members GO Category GO:0045910 negative regulation of DNA recombination Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0000403 Y-form DNA binding Database 0.04
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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