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Query: RAB6A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB6A 0 3.395 -1.080 1.980 1.078 -1.682
RAB6A 0 3.395 -1.080 1.980 0.752 0.721

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB6A Ubiquitylation K144 0.298 0.546 _EEAEK(gl)LSADCGMK_
RAB6A Phosphorylation S2 -0.159 -0.138 _(ac)S(ph)TGGDFGNPLRK_
RAB6A Phosphorylation T3 -0.614 -0.138 _(ac)ST(ph)GGDFGNPLR_
RAB6A Ubiquitylation K180 -0.955 _DIYELIK(gl)K_

Background Information for RAB6A:


Pubmed-RAB6A »
Uniprot-RAB6A »
Biogrid-RAB6A »
ProteomicsDB-RAB6A »

Tumorportal-RAB6A »
COSMIC-RAB6A »
GenomeRNAi-RAB6A »
Genecards-RAB6A


Protein-protein Interactions for RAB6A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GDI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OCRL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB6A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13


Protein complexes (CORUM database) featuring RAB6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0034067 protein localization to Golgi apparatus Database 0.27
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0000042 protein targeting to Golgi Database 0.2
Category members Pathway Pathway_1273 BIOCARTA_RAB_PATHWAY 0 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0018125 peptidyl-cysteine methylation Database 0.09
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0006890 retrograde vesicle-mediated transport, Golgi to ER Database 0.05
Category members Pathway Pathway_108 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0


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