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Query: PTPN23

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTPN23 0 -3.267 0.800 -0.570

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTPN23 Ubiquitylation K288 -0.754 -0.795 _LAK(gl)GQPDTVQDALR_
PTPN23 Phosphorylation S1123 -1.317 -0.838 _GAAAADLLSSS(ph)PESQHGGTQSPGGGQPLLQPTK_
PTPN23 Ubiquitylation K215 -0.317 _ISAQVVDYYK(gl)EACR_
PTPN23 Ubiquitylation K500 -0.529 _EWAK(gl)YMEVHEK_

Background Information for PTPN23:


Pubmed-PTPN23 »
Uniprot-PTPN23 »
Biogrid-PTPN23 »
ProteomicsDB-PTPN23 »

Tumorportal-PTPN23 »
COSMIC-PTPN23 »
GenomeRNAi-PTPN23 »
Genecards-PTPN23


Protein-protein Interactions for PTPN23
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF20A Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTPN23
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Tyr_Pase_cat IPR003595 0
Category members BRO1_dom IPR004328 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring PTPN23
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTPN23
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Database 0.09
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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