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Query: PREB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PREB 0 -1.217 0.820 -0.890 -0.364 -0.232

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PREB Ubiquitylation K218 -0.621 _DLK(gl)ASVWQK_
PREB Ubiquitylation K272 -1.012 _LFTVQIPHK(gl)R_

Background Information for PREB:


Pubmed-PREB »
Uniprot-PREB »
Biogrid-PREB »
ProteomicsDB-PREB »

Tumorportal-PREB »
COSMIC-PREB »
GenomeRNAi-PREB »
Genecards-PREB


Protein-protein Interactions for PREB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ICOSLG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OCLN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PREB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring PREB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PREB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members Pathway Pathway_115 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0048208 COPII vesicle coating Database 0


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