bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PIK3C2A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIK3C2A 0 0.713 0.620 -0.690 -0.145 0.459

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIK3C2A Phosphorylation S338 0.437 0.685 _SQS(ph)LNIR_
PIK3C2A Phosphorylation S259 1.013 0.488 _VSNLQVS(ph)PK_
PIK3C2A Phosphorylation S1553 0.393 0.261 _SADAGSFS(ph)PTPGQIGGAVK_
PIK3C2A Ubiquitylation K11 -1.238 -0.061 _(ac)AQISSNSGFK(gl)ECPSSHPEPTR_
PIK3C2A Ubiquitylation K674 -0.351 _SPTDCAQSSK(gl)SVK_
PIK3C2A Ubiquitylation K112 -0.649 _LLLDDSFETK(gl)K_
PIK3C2A Ubiquitylation K113 -0.649 _LLLDDSFETK(gl)K_

Background Information for PIK3C2A:


Pubmed-PIK3C2A »
Uniprot-PIK3C2A »
Biogrid-PIK3C2A »
ProteomicsDB-PIK3C2A »

Tumorportal-PIK3C2A »
COSMIC-PIK3C2A »
GenomeRNAi-PIK3C2A »
Genecards-PIK3C2A


Protein-protein Interactions for PIK3C2A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait ARX Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PICALM Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNJL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLINT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM136A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PICALM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAMBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAMBPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PIK3C2A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members PI3/4_kinase_cat_dom IPR000403 1.52
Category members Phox IPR001683 0.24
Category members PI3K_Ras-bd_dom IPR000341 0.19
Category members PInositide-3_kin_accessory_dom IPR001263 0.13
Category members PI3K_C2_dom IPR002420 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members C2_dom IPR000008 0


Protein complexes (CORUM database) featuring PIK3C2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1185 EGFR-containing signaling complex Database 0


Categories featuring PIK3C2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members Pathway Pathway_501 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0046854 phosphatidylinositol phosphorylation Database 0.31
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity Database 0.19
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members Pathway Pathway_521 PID_AVB3_INTEGRIN_PATHWAY 0 0.03
Category members GO Category GO:0031982 vesicle Database 0.01
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_102 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 0 0
Category members Pathway Pathway_104 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE 0 0
Category members Pathway Pathway_105 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0005942 phosphatidylinositol 3-kinase complex Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0014829 vascular smooth muscle contraction Database 0
Category members GO Category GO:0016303 1-phosphatidylinositol-3-kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0035004 phosphatidylinositol 3-kinase activity Database 0
Category members GO Category GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process Database 0
Category members GO Category GO:0048008 platelet-derived growth factor receptor signaling pathway Database 0
Category members GO Category GO:0048268 clathrin coat assembly Database 0


.

© Copyright Svejstrup Laboratory 2015