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Query: PHKG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHKG2 0 0.212 -0.370 -0.400
PHKG2 0 0.212 -0.350 -0.370

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHKG2 Ubiquitylation K265 0.212 _SSTVK(gl)DLISR_

Background Information for PHKG2:


Pubmed-PHKG2 »
Uniprot-PHKG2 »
Biogrid-PHKG2 »
ProteomicsDB-PHKG2 »

Tumorportal-PHKG2 »
COSMIC-PHKG2 »
GenomeRNAi-PHKG2 »
Genecards-PHKG2


Protein-protein Interactions for PHKG2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PHKG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1R3B Cat. description Hein, Mann, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEANC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHKG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Phosph_kin_gamma IPR002291 0
Category members LipoPS_kinase IPR010440 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PHKG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PHKG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_66 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS 0 0.22
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0005980 glycogen catabolic process Database 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0004689 phosphorylase kinase activity Database 0.08
Category members GO Category GO:0005977 glycogen metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0005978 glycogen biosynthetic process Database 0.04
Category members GO Category GO:0050321 tau-protein kinase activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Disease phenotype Glycogen_storage_disease_due_to_liver_phosphorylase_kinase_deficiency Glycogen storage disease due to liver phosphorylase kinase deficiency Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0005964 phosphorylase kinase complex Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0045819 positive regulation of glycogen catabolic process Database 0


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