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Query: PHF12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHF12 1 8.239 -0.980 1.740

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHF12 Phosphorylation T129 5.544 _RT(ph)T(ph)SPS(ph)SDTDLLDRS(ph)ASK_
PHF12 Phosphorylation T130 5.544 _RT(ph)T(ph)SPS(ph)SDTDLLDRS(ph)ASK_
PHF12 Phosphorylation S133 5.544 _RT(ph)T(ph)SPS(ph)SDTDLLDRS(ph)ASK_
PHF12 Phosphorylation S142 5.544 _RT(ph)T(ph)SPS(ph)SDTDLLDRS(ph)ASK_
PHF12 Phosphorylation S977 0.955 0.941 _GDAS(ph)LLQDGVLAEK_
PHF12 Phosphorylation S131 0.403 0.428 _TTS(ph)PSSDTDLLDR_
PHF12 Phosphorylation T671 -0.003 -0.158 _VLT(ph)PPQAAGDGILATTANQR_

Background Information for PHF12:


Pubmed-PHF12 »
Uniprot-PHF12 »
Biogrid-PHF12 »
ProteomicsDB-PHF12 »

Tumorportal-PHF12 »
COSMIC-PHF12 »
GenomeRNAi-PHF12 »
Genecards-PHF12


Protein-protein Interactions for PHF12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GATAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KDM5A Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3B Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBBP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHF12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FHA_dom IPR000253 2.3
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members SMAD_FHA_domain IPR008984 0.86


Protein complexes (CORUM database) featuring PHF12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PHF12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0016580 Sin3 complex Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0001106 RNA polymerase II transcription corepressor activity Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0001222 transcription corepressor binding Database 0


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