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Query: PEX5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PEX5 0 -1.285 -0.220 0.060 -0.723

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PEX5 Ubiquitylation K238 -0.622 _LANSEFLK(gl)FVR_

Background Information for PEX5:


Pubmed-PEX5 »
Uniprot-PEX5 »
Biogrid-PEX5 »
ProteomicsDB-PEX5 »

Tumorportal-PEX5 »
COSMIC-PEX5 »
GenomeRNAi-PEX5 »
Genecards-PEX5


Protein-protein Interactions for PEX5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP2M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEU2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PEX5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93


Protein complexes (CORUM database) featuring PEX5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PEX5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006625 protein targeting to peroxisome Database 0.35
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0007029 endoplasmic reticulum organization Database 0.05
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Disease phenotype adrenoleukodystrophy_neonatal_(NALD) adrenoleukodystrophy neonatal (NALD) Database 0
Category members Disease phenotype Infantile_Refsum_disease Infantile Refsum disease Database 0
Category members Disease phenotype infantile_Refsum_disease_(IRD) infantile Refsum disease (IRD) Database 0
Category members Disease phenotype NEONATAL_ADRENOLEUKODYSTROPHY NEONATAL ADRENOLEUKODYSTROPHY Database 0
Category members Disease phenotype ZELLWEGER_SYNDROME ZELLWEGER SYNDROME Database 0
Category members Disease phenotype Zellweger_syndrome_(ZWS) Zellweger syndrome (ZWS) Database 0
Category members GO Category GO:0000038 very long-chain fatty acid metabolic process Database 0
Category members GO Category GO:0000268 peroxisome targeting sequence binding Database 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0005052 peroxisome matrix targeting signal-1 binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006635 fatty acid beta-oxidation Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0007006 mitochondrial membrane organization Database 0
Category members GO Category GO:0007031 peroxisome organization Database 0
Category members GO Category GO:0016558 protein import into peroxisome matrix Database 0
Category members GO Category GO:0016560 protein import into peroxisome matrix, docking Database 0
Category members GO Category GO:0016561 protein import into peroxisome matrix, translocation Database 0
Category members GO Category GO:0021795 cerebral cortex cell migration Database 0
Category members GO Category GO:0021895 cerebral cortex neuron differentiation Database 0
Category members GO Category GO:0031267 small GTPase binding Database 0
Category members GO Category GO:0040018 positive regulation of multicellular organism growth Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0045046 protein import into peroxisome membrane Database 0
Category members GO Category GO:0048468 cell development Database 0
Category members GO Category GO:0050905 neuromuscular process Database 0


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