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Query: PAM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAM 1 0.858 0.410 -0.620

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAM Phosphorylation S918 0.585 1.654 _GKGS(ph)GGLNLGNFFASR_
PAM Ubiquitylation K716 -1.381 _TDTK(gl)EFVR_

Background Information for PAM:


Pubmed-PAM »
Uniprot-PAM »
Biogrid-PAM »
ProteomicsDB-PAM »

Tumorportal-PAM »
COSMIC-PAM »
GenomeRNAi-PAM »
Genecards-PAM


Protein-protein Interactions for PAM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait B3GNT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cu2_ascorb_mOase_N IPR000323 0
Category members NHL_repeat IPR001258 0
Category members PHM/PNGase_F_dom IPR008977 0
Category members NHL_repeat_subgr IPR013017 0


Protein complexes (CORUM database) featuring PAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0032956 regulation of actin cytoskeleton organization Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0030141 secretory granule Database 0.11
Category members GO Category GO:0042476 odontogenesis Database 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0030667 secretory granule membrane Database 0.05
Category members GO Category GO:0043204 perikaryon Database 0.05
Category members GO Category GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen Database 0.05
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0004497 monooxygenase activity Database 0.04
Category members GO Category GO:0009268 response to pH Database 0.01
Category members GO Category GO:0001519 peptide amidation Database 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0001676 long-chain fatty acid metabolic process Database 0
Category members GO Category GO:0005507 copper ion binding Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006518 peptide metabolic process Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007595 lactation Database 0
Category members GO Category GO:0009404 toxin metabolic process Database 0
Category members GO Category GO:0019538 protein metabolic process Database 0
Category members GO Category GO:0022602 ovulation cycle process Database 0
Category members GO Category GO:0031418 L-ascorbic acid binding Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0046688 response to copper ion Database 0
Category members GO Category GO:0050708 regulation of protein secretion Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0060135 maternal process involved in female pregnancy Database 0
Category members GO Category GO:0060173 limb development Database 0


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