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Query: MKS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MKS1 0 0.853

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MKS1 Ubiquitylation K178 -0.574 0.716 _GMEGGILK(gl)SR_
MKS1 Ubiquitylation K507 0.137 -0.095 _AFMESSSLQK(gl)R_
MKS1 Ubiquitylation K469 -0.213 _IPGSFK(gl)GER_

Background Information for MKS1:





Protein-protein Interactions for MKS1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYBA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPIAL4G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAD51L3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MKS1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members B9_dom IPR010796 0


Protein complexes (CORUM database) featuring MKS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MKS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0016020 membrane Database 0.52
Category members Disease phenotype Joubert_syndrome_with_ocular_defect Joubert syndrome with ocular defect Database 0.08
Category members Disease phenotype JOUBERT_SYNDROME JOUBERT SYNDROME Database 0.07
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members Disease phenotype Meckel_syndrome Meckel syndrome Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0035869 ciliary transition zone Database 0
Category members GO Category GO:0036038 TCTN-B9D complex Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0048754 branching morphogenesis of an epithelial tube Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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