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Query: LRPPRC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRPPRC 0 0.589 0.110 -0.740 -0.075 0.032 -0.336 0.525 0.443

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for LRPPRC:


Pubmed-LRPPRC »
Uniprot-LRPPRC »
Biogrid-LRPPRC »
ProteomicsDB-LRPPRC »

Tumorportal-LRPPRC »
COSMIC-LRPPRC »
GenomeRNAi-LRPPRC »
Genecards-LRPPRC


Protein-protein Interactions for LRPPRC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRPPRC Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015


Protein Domains in LRPPRC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pentatricopeptide_repeat IPR002885 0


Protein complexes (CORUM database) featuring LRPPRC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring LRPPRC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005637 nuclear inner membrane Database 1.98
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0000794 condensed nuclear chromosome Database 1.58
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0047497 mitochondrion transport along microtubule Database 0.23
Category members GO Category GO:0005640 nuclear outer membrane Database 0.18
Category members GO Category GO:0048487 beta-tubulin binding Database 0.1
Category members GO Category GO:0000961 negative regulation of mitochondrial RNA catabolic process Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0070129 regulation of mitochondrial translation Database 0


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