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Query: LIN28A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LIN28A 0 -0.047 0.700 -0.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LIN28A Ubiquitylation K102 -0.047 _SAK(gl)GLESIR_

Background Information for LIN28A:


Pubmed-LIN28A »
Uniprot-LIN28A »
Biogrid-LIN28A »
ProteomicsDB-LIN28A »

Tumorportal-LIN28A »
COSMIC-LIN28A »
GenomeRNAi-LIN28A »
Genecards-LIN28A


Protein-protein Interactions for LIN28A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIN28A Cat. description Hein, Mann, Cell 2015


Protein Domains in LIN28A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members Znf_CCHC IPR001878 1.51
Category members CSP_DNA-bd IPR002059 0.04
Category members Cold_shock_prot IPR011129 0.04


Protein complexes (CORUM database) featuring LIN28A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LIN28A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0019827 stem cell maintenance Database 0.48
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0031369 translation initiation factor binding Database 0.1
Category members GO Category GO:0000932 cytoplasmic mRNA processing body Database 0.08
Category members GO Category GO:0010586 miRNA metabolic process Database 0.05
Category members GO Category GO:0031054 pre-miRNA processing Database 0.01
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007281 germ cell development Database 0
Category members GO Category GO:0010587 miRNA catabolic process Database 0
Category members GO Category GO:0031123 RNA 3'-end processing Database 0
Category members GO Category GO:0035198 miRNA binding Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0045686 negative regulation of glial cell differentiation Database 0
Category members GO Category GO:0045727 positive regulation of translation Database 0
Category members GO Category GO:0048863 stem cell differentiation Database 0
Category members GO Category GO:0060964 regulation of gene silencing by miRNA Database 0


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