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Query: KLK6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KLK6 0 -7.255 -0.160 -0.280

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for KLK6:


Pubmed-KLK6 »
Uniprot-KLK6 »
Biogrid-KLK6 »
ProteomicsDB-KLK6 »

Tumorportal-KLK6 »
COSMIC-KLK6 »
GenomeRNAi-KLK6 »
Genecards-KLK6


Protein-protein Interactions for KLK6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CPSF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KLK6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_S1A_nudel IPR015420 0.15
Category members Trypsin-like_Pept_dom IPR009003 0.04
Category members Peptidase_S1A IPR001314 0.03
Category members Peptidase_S1 IPR001254 0.01


Protein complexes (CORUM database) featuring KLK6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KLK6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030574 collagen catabolic process Database 0.2
Category members GO Category GO:0042552 myelination Database 0.16
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0042982 amyloid precursor protein metabolic process Database 0.04
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0009611 response to wounding Database 0
Category members GO Category GO:0010975 regulation of neuron projection development Database 0
Category members GO Category GO:0016540 protein autoprocessing Database 0
Category members GO Category GO:0042246 tissue regeneration Database 0
Category members GO Category GO:0042445 hormone metabolic process Database 0
Category members GO Category GO:0045595 regulation of cell differentiation Database 0
Category members GO Category GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway Database 0


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