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Query: KHDRBS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KHDRBS1 1 8.582 -0.370 -0.090
KHDRBS1 1 8.582 -0.370 -0.090 -0.648 -1.258 -0.381 -0.646 -0.079

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KHDRBS1 Ubiquitylation K169 -0.739 0.728 _QYPK(gl)FNFVGK_
KHDRBS1 Ubiquitylation K185 0.103 0.578 _ILGPQGNTIK(gl)R_
KHDRBS1 Ubiquitylation K165 -0.612 0.332 _VLIPVK(gl)QYPK_
KHDRBS1 Phosphorylation S20 0.944 -0.215 _SGS(ph)M(ox)DPSGAHPSVR_
KHDRBS1 Phosphorylation S18 0.745 -0.921 _S(ph)GSM(ox)DPSGAHPSVR_
KHDRBS1 Phosphorylation S58 9.021 _AS(ph)PATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK_
KHDRBS1 Ubiquitylation K194 0.511 _LQEETGAK(gl)ISVLGK_
KHDRBS1 Ubiquitylation K432 -1.686 _APPARPVK(gl)GAYR_

Background Information for KHDRBS1:


Pubmed-KHDRBS1 »
Uniprot-KHDRBS1 »
Biogrid-KHDRBS1 »
ProteomicsDB-KHDRBS1 »

Tumorportal-KHDRBS1 »
COSMIC-KHDRBS1 »
GenomeRNAi-KHDRBS1 »
Genecards-KHDRBS1


Protein-protein Interactions for KHDRBS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait KHDRBS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KHDRBS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring KHDRBS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2577 Sam68-p85 P13K-IRS-1-IR signaling complex Database 0.04
Category members Corum 2578 Sam68-p120GAP complex Database 0
Category members Corum 644 ASPP1-SAM68 complex Database 0


Categories featuring KHDRBS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0045948 positive regulation of translational initiation Database 0
Category members GO Category GO:0046831 regulation of RNA export from nucleus Database 0
Category members GO Category GO:0046833 positive regulation of RNA export from nucleus Database 0


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