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Query: IFT80

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFT80 1 2.099 -1.610 2.740

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IFT80 Ubiquitylation K665 -0.641 _DLCITSVK(gl)R_

Background Information for IFT80:


Pubmed-IFT80 »
Uniprot-IFT80 »
Biogrid-IFT80 »
ProteomicsDB-IFT80 »

Tumorportal-IFT80 »
COSMIC-IFT80 »
GenomeRNAi-IFT80 »
Genecards-IFT80


Protein-protein Interactions for IFT80
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CORO1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC30A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IFT80
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring IFT80
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IFT80
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0007224 smoothened signaling pathway Database 2.11
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0060349 bone morphogenesis Database 0.17
Category members GO Category GO:0002062 chondrocyte differentiation Database 0.13
Category members GO Category GO:0045880 positive regulation of smoothened signaling pathway Database 0.01
Category members Disease phenotype Jeune_syndrome Jeune syndrome Database 0
Category members Disease phenotype Short_rib-polydactyly_syndrome_Verma-Naumoff_type Short rib-polydactyly syndrome Verma-Naumoff type Database 0
Category members GO Category GO:0001649 osteoblast differentiation Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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