Results for the Category
positive regulation of smoothened signaling pathway
(GO:0045880)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| CTNNA1 | 1 | -0.520 | 1.660 | -0.690 | -1.164 | |||
| CTNNA1 | 1 | -0.520 | 1.660 | 0.139 | 0.436 | 0.323 | ||
| IFT80 | 1 | -1.610 | 2.740 | |||||
| SMO | 1 | -0.690 | 1.110 | 1.532 | ||||
| POR | 0 | -0.930 | 1.670 | 0.409 | 0.260 | 0.035 | ||
| FOXA1 | 0 | 1.190 | -0.010 | |||||
| KIF7 | 0 | -0.700 | 0.600 | 0.688 | ||||
| KIF7 | 0 | 0.280 | -0.500 | 0.688 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CTNNA1 | Ubiquitylation | K16 | -0.194 | -0.141 | _WDPK(gl)SLEIR_ |
| CTNNA1 | Ubiquitylation | K45 | -1.131 | -0.728 | _LLEPLVTQVTTLVNTNSK(gl)GPSNK_ |
| CTNNA1 | Ubiquitylation | K120 | -0.333 | _AAAGEFADDPCSSVK(gl)R_ | |
| CTNNA1 | Ubiquitylation | K414 | 0.977 | _NGNEK(gl)EVKEYAQVFR_ | |
| CTNNA1 | Ubiquitylation | K417 | 0.211 | _NGNEK(gl)EVKEYAQVFR_ | |
| CTNNA1 | Phosphorylation | S641 | -0.056 | 0.089 | _TPEELDDS(ph)DFETEDFDVR_ |
| CTNNA1 | Phosphorylation | T654 | 0.808 | 0.392 | _SRT(ph)SVQTEDDQLIAGQSAR_ |
| CTNNA1 | Phosphorylation | S655 | 1.043 | 0.882 | _SRTS(ph)VQTEDDQLIAGQSAR_ |
| CTNNA1 | Ubiquitylation | K683 | 3.760 | -0.837 | _AIMAQLPQEQKAK(gl)_ |
| CTNNA1 | Ubiquitylation | K747 | -0.384 | _NTSDVISAAK(gl)K_ | |
| CTNNA1 | Ubiquitylation | K748 | -0.083 | -0.384 | _NTSDVISAAKK(gl)_ |
| FOXA1 | Phosphorylation | S331 | -0.760 | -0.866 | _TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK_ |
| IFT80 | Ubiquitylation | K665 | -0.641 | _DLCITSVK(gl)R_ | |
| KIF7 | Ubiquitylation | K1208 | 0.476 | _YMWINQELK(gl)QK_ |
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