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Query: HOOK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HOOK1 0 -1.201 1.180 -1.060

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HOOK1 Ubiquitylation K678 0.231 _SLAFQK(gl)LGMESR_
HOOK1 Phosphorylation S719 -0.815 -0.265 _NLS(ph)VKVPATTSD_
HOOK1 Ubiquitylation K612 -0.788 _MYLEK(gl)AR_
HOOK1 Ubiquitylation K424 -0.352 _DTLK(gl)ETNEELR_

Background Information for HOOK1:


Pubmed-HOOK1 »
Uniprot-HOOK1 »
Biogrid-HOOK1 »
ProteomicsDB-HOOK1 »

Tumorportal-HOOK1 »
COSMIC-HOOK1 »
GenomeRNAi-HOOK1 »
Genecards-HOOK1


Protein-protein Interactions for HOOK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AKTIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ALOXE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HERC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOOK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGGTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SELENBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HOOK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Hook-related_fam IPR008636 0.13
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring HOOK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HOOK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0008333 endosome to lysosome transport Database 0.49
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0030897 HOPS complex Database 0.13
Category members GO Category GO:0007032 endosome organization Database 0.11
Category members GO Category GO:0070695 FHF complex Database 0.1
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0045022 early endosome to late endosome transport Database 0


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