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Query: HIPK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIPK1 0 -0.246 1.760 -0.820

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIPK1 Ubiquitylation K492 -0.060 _YISQTQGLPAEYLLSAGTK(gl)TTR_
HIPK1 Phosphorylation S1271 -0.186 _GSTIYTGYPLS(ph)PTK_
HIPK1 Ubiquitylation K614 -0.350 _SCFQNMEICK(gl)R_

Background Information for HIPK1:


Pubmed-HIPK1 »
Uniprot-HIPK1 »
Biogrid-HIPK1 »
ProteomicsDB-HIPK1 »

Tumorportal-HIPK1 »
COSMIC-HIPK1 »
GenomeRNAi-HIPK1 »
Genecards-HIPK1


Protein-protein Interactions for HIPK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FHL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIPK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring HIPK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIPK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0007224 smoothened signaling pathway Database 2.11
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Database 0.83
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0060216 definitive hemopoiesis Database 0.18
Category members GO Category GO:0010842 retina layer formation Database 0.06
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0048596 embryonic camera-type eye morphogenesis Database 0.01
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016926 protein desumoylation Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0060059 embryonic retina morphogenesis in camera-type eye Database 0
Category members GO Category GO:0060235 lens induction in camera-type eye Database 0
Category members GO Category GO:0061072 iris morphogenesis Database 0


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