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Query: GTF2F1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTF2F1 0 -0.632 -0.280 0.230 -3.106 1.494 -0.308

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTF2F1 Phosphorylation T445 0.385 0.574 _T(ph)TPNSGDVQVTEDAVR_
GTF2F1 Phosphorylation T446 0.385 0.574 _T(ph)TPNSGDVQVTEDAVR_
GTF2F1 Phosphorylation S385 0.043 0.017 _GNS(ph)RPGT(ph)PSAEGGSTSSTLR_
GTF2F1 Phosphorylation S391 -0.032 -0.039 _GNS(ph)RPGTPS(ph)AEGGSTSSTLR_
GTF2F1 Phosphorylation T389 0.484 -0.150 _GNS(ph)RPGT(ph)PSAEGGSTSSTLR_
GTF2F1 Phosphorylation S433 -0.395 -0.554 _LDTGPQSLS(ph)GK_

Background Information for GTF2F1:


Pubmed-GTF2F1 »
Uniprot-GTF2F1 »
Biogrid-GTF2F1 »
ProteomicsDB-GTF2F1 »

Tumorportal-GTF2F1 »
COSMIC-GTF2F1 »
GenomeRNAi-GTF2F1 »
Genecards-GTF2F1


Protein-protein Interactions for GTF2F1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF2B Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIPI2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf124 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1QTNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DSCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDH20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPANXA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTF2F1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TFIIF_interaction IPR011039 0.29


Protein complexes (CORUM database) featuring GTF2F1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2825 BRCA1-RNA polymerase II complex Database 1.38
Category members Corum 103 RNA polymerase II holoenzyme complex Database 1.07
Category members Corum 3066 RNA polymerase II complex, chromatin structure modifying Database 0.92
Category members Corum 3064 RNA polymerase II complex, chromatin structure modifying Database 0.64
Category members Corum 3067 RNA polymerase II complex, incomplete (CDK8 complex), chromatin structure modifying Database 0.63
Category members Corum 3060 RNA polymerase II complex (RPB1, RAP74, CDK8, CYCC, SRB7, BAF190, BAF47), chromatin structure modifying Database 0.35
Category members Corum 153 TFIIF complex (transcription factor IIF) Database 0.29
Category members Corum 2685 RNA polymerase II (RNAPII) Database 0.12
Category members Corum 810 FCP1-associated protein complex Database 0.1
Category members Corum 811 FCP1-associated protein complex Database 0.1
Category members Corum 5363 Actin-ribonucleoprotein complex (POLR2A, GTF2F1, HNRNPU) Database 0.06


Categories featuring GTF2F1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0050434 positive regulation of viral transcription Database 4.8
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members Pathway Pathway_360 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 0 3.35
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members Pathway Pathway_367 REACTOME_ELONGATION_ARREST_AND_RECOVERY 0 1.67
Category members Pathway Pathway_361 REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX 0 1.57
Category members Pathway Pathway_362 REACTOME_MRNA_CAPPING 0 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0006370 7-methylguanosine mRNA capping Database 1.26
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_364 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT 0 0.35
Category members Pathway Pathway_370 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING 0 0.34
Category members GO Category GO:0005674 transcription factor TFIIF complex Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_358 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_381 BIOCARTA_RARRXR_PATHWAY 0 0.08
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0019211 phosphatase activator activity Database 0
Category members GO Category GO:0030054 cell junction Database 0


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