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Query: FBN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBN2 1 1.684 1.100 -0.880

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBN2 Ubiquitylation K385 1.550 _MTK(gl)MQCCCEPGR_
FBN2 Ubiquitylation K712 0.133 1.523 _STCYGGIKK(gl)_
FBN2 Ubiquitylation K1582 0.690 _VGNCYLK(gl)FGPR_

Background Information for FBN2:


Pubmed-FBN2 »
Uniprot-FBN2 »
Biogrid-FBN2 »
ProteomicsDB-FBN2 »

Tumorportal-FBN2 »
COSMIC-FBN2 »
GenomeRNAi-FBN2 »
Genecards-FBN2


Protein-protein Interactions for FBN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAMTSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXD4L6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWCE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF408 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members EGF-like_Ca-bd_dom IPR001881 0.69
Category members Cadherin-like IPR015919 0.21
Category members FBN/EtMIC4 IPR011398 0
Category members TB_dom IPR017878 0


Protein complexes (CORUM database) featuring FBN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FBN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005201 extracellular matrix structural constituent Database 0.55
Category members GO Category GO:0005578 proteinaceous extracellular matrix Database 0.53
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0001527 microfibril Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030501 positive regulation of bone mineralization Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0035583 sequestering of TGFbeta in extracellular matrix Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0060346 bone trabecula formation Database 0


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