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Query: EXO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EXO1 0 0.826 0.890 -0.810

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EXO1 Phosphorylation S598 0.826 _TIS(ph)PPTLGTLR_

Background Information for EXO1:


Pubmed-EXO1 »
Uniprot-EXO1 »
Biogrid-EXO1 »
ProteomicsDB-EXO1 »

Tumorportal-EXO1 »
COSMIC-EXO1 »
GenomeRNAi-EXO1 »
Genecards-EXO1


Protein-protein Interactions for EXO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait COMT Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EXO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members XPG-I_dom IPR006086 0.17
Category members HhH2 IPR008918 0.17
Category members 5-3_exonuclease_C IPR020045 0.17
Category members XPG_DNA_repair_N IPR006085 0
Category members PIN_domain-like IPR029060 0


Protein complexes (CORUM database) featuring EXO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 424 EXO1-MLH1-PCNA complex Database 0.17
Category members Corum 415 EXO1-MLH1-PMS2 complex Database 0
Category members Corum 423 EXO1-MLH1-PMS2 complex Database 0


Categories featuring EXO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_341 KEGG_MISMATCH_REPAIR 0 1.02
Category members GO Category GO:0006298 mismatch repair Database 0.33
Category members GO Category GO:0008409 5'-3' exonuclease activity Database 0.13
Category members GO Category GO:0045190 isotype switching Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0004518 nuclease activity Database 0.09
Category members GO Category GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity Database 0.04
Category members GO Category GO:0048256 flap endonuclease activity Database 0.04
Category members GO Category GO:0007126 meiosis Database 0.01
Category members GO Category GO:0002455 humoral immune response mediated by circulating immunoglobulin Database 0
Category members GO Category GO:0004523 ribonuclease H activity Database 0
Category members GO Category GO:0004527 exonuclease activity Database 0
Category members GO Category GO:0016446 somatic hypermutation of immunoglobulin genes Database 0
Category members GO Category GO:0043566 structure-specific DNA binding Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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