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Query: EPS8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPS8 0 -0.093 -0.740 0.680
EPS8 0 -0.093 -0.740 0.680 1.272

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPS8 Phosphorylation S625 -2.045 _PADTPPAPS(ph)PPPTPAPVPVPLPPSTPAPVPVSK_

Background Information for EPS8:





Protein-protein Interactions for EPS8

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPS8

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members PTB/PI_dom IPR006020 0
Category members PTB IPR013625 0
Category members SAM/pointed IPR013761 0


Protein complexes (CORUM database) featuring EPS8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPS8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0032587 ruffle membrane Database 0.65
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0051016 barbed-end actin filament capping Database 0.21
Category members GO Category GO:0010458 exit from mitosis Database 0.2
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members GO Category GO:0048149 behavioral response to ethanol Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members Disease phenotype Autosomal_recessive_nonsyndromic_sensorineural_deafness_type_DFNB Autosomal recessive nonsyndromic sensorineural deafness type DFNB Database 0.04
Category members Pathway Pathway_1157 PID_RAC1_REG_PATHWAY 0 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008344 adult locomotory behavior Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0
Category members GO Category GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex Database 0
Category members GO Category GO:0030832 regulation of actin filament length Database 0
Category members GO Category GO:0032420 stereocilium Database 0
Category members GO Category GO:0036336 dendritic cell migration Database 0
Category members GO Category GO:0051764 actin crosslink formation Database 0
Category members GO Category GO:0070358 actin polymerization-dependent cell motility Database 0


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