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Query: DPYSL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DPYSL3 0 -1.203 0.400 -0.420 -0.511

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DPYSL3 Phosphorylation T623 -0.604 -0.464 _GM(ox)YDGPVFDLTTT(ph)PK_
DPYSL3 Phosphorylation S636 -0.777 -0.696 _GS(ph)PTRPNPPVR_
DPYSL3 Phosphorylation S102 -1.104 -0.731 _EESREPAPAS(ph)PAPAGVEIR_
DPYSL3 Phosphorylation T622 -0.228 _GM(ox)YDGPVFDLTT(ph)TPK_

Background Information for DPYSL3:


Pubmed-DPYSL3 »
Uniprot-DPYSL3 »
Biogrid-DPYSL3 »
ProteomicsDB-DPYSL3 »

Tumorportal-DPYSL3 »
COSMIC-DPYSL3 »
GenomeRNAi-DPYSL3 »
Genecards-DPYSL3


Protein-protein Interactions for DPYSL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ODF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDCA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPYS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPYSL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPYSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLK1S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRDM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRP7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DPYSL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Hydantoinase/dihydroPyrase IPR011778 0.23
Category members Amidohydro_1 IPR006680 0
Category members Metal-dep_hydrolase_composite IPR011059 0


Protein complexes (CORUM database) featuring DPYSL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DPYSL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0030426 growth cone Database 1.61
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0035374 chondroitin sulfate binding Database 0.44
Category members GO Category GO:0051219 phosphoprotein binding Database 0.33
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0006208 pyrimidine nucleobase catabolic process Database 0.22
Category members Disease phenotype Amyotrophic_lateral_sclerosis Amyotrophic lateral sclerosis Database 0.21
Category members Pathway Pathway_1282 REACTOME_CRMPS_IN_SEMA3A_SIGNALING 0 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0010976 positive regulation of neuron projection development Database 0.05
Category members GO Category GO:0010977 negative regulation of neuron projection development Database 0.04
Category members GO Category GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Database 0.04
Category members GO Category GO:0031941 filamentous actin Database 0.01
Category members GO Category GO:0048678 response to axon injury Database 0.01
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0044297 cell body Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0051491 positive regulation of filopodium assembly Database 0
Category members GO Category GO:0051764 actin crosslink formation Database 0
Category members GO Category GO:0070382 exocytic vesicle Database 0
Category members GO Category GO:0071345 cellular response to cytokine stimulus Database 0


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