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Query: DHCR7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHCR7 0 1.761 -0.384 0.267 0.288

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHCR7 Phosphorylation S14 0.877 0.606 _S(ph)LDGVTNDR_
DHCR7 Ubiquitylation K13 -0.522 0.107 _AK(gl)SLDGVTNDR_
DHCR7 Ubiquitylation K88 -0.930 -0.171 _LSDIWAK(gl)TPPITR_
DHCR7 Ubiquitylation K4 -0.994 _(ac)AAK(gl)SQPNIPK_

Background Information for DHCR7:


Pubmed-DHCR7 »
Uniprot-DHCR7 »
Biogrid-DHCR7 »
ProteomicsDB-DHCR7 »

Tumorportal-DHCR7 »
COSMIC-DHCR7 »
GenomeRNAi-DHCR7 »
Genecards-DHCR7


Protein-protein Interactions for DHCR7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPA14 Cat. description Hein, Mann, Cell 2015
Category members IP bait LTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015


Protein Domains in DHCR7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ergosterol_biosynth_ERG4_ERG24 IPR001171 0.46


Protein complexes (CORUM database) featuring DHCR7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHCR7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005640 nuclear outer membrane Database 0.18
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Database 0.03
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0016126 sterol biosynthetic process Database 0
Category members GO Category GO:0045540 regulation of cholesterol biosynthetic process Database 0


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