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Query: DCLK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DCLK1 0 2.917 -1.340 1.710

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DCLK1 Phosphorylation S353 0.566 _DLYRPLSS(ph)DDLDSVGDSV_
DCLK1 Phosphorylation S352 0.103 0.523 _DLYRPLS(ph)SDDLDSVGDSV_
DCLK1 Phosphorylation S352 0.641 0.487 _SSQHGGS(ph)STSLASTK_
DCLK1 Phosphorylation S32 0.456 0.202 _VNGLPS(ph)PTHSAHCSFYR_
DCLK1 Phosphorylation S337 -0.893 -0.694 _SPSPSPTS(ph)PGSLR_
DCLK1 Phosphorylation T336 -1.793 _SPSPSPT(ph)SPGSLR_

Background Information for DCLK1:


Pubmed-DCLK1 »
Uniprot-DCLK1 »
Biogrid-DCLK1 »
ProteomicsDB-DCLK1 »

Tumorportal-DCLK1 »
COSMIC-DCLK1 »
GenomeRNAi-DCLK1 »
Genecards-DCLK1


Protein-protein Interactions for DCLK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDCA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DCLK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Doublecortin_dom IPR003533 0
Category members Doublecortin_chordata IPR017302 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring DCLK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DCLK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0048813 dendrite morphogenesis Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0048675 axon extension Database 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0005057 receptor signaling protein activity Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0021952 central nervous system projection neuron axonogenesis Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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