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Query: COX6B1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
COX6B1 0 0.981 0.040 0.480 0.423

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
COX6B1 Ubiquitylation K13 -1.330 0.150 _NYK(gl)TAPFDSR_
COX6B1 Ubiquitylation K47 -0.072 _AMTAK(gl)GGDISVCEWYQR_

Background Information for COX6B1:


Pubmed-COX6B1 »
Uniprot-COX6B1 »
Biogrid-COX6B1 »
ProteomicsDB-COX6B1 »

Tumorportal-COX6B1 »
COSMIC-COX6B1 »
GenomeRNAi-COX6B1 »
Genecards-COX6B1


Protein-protein Interactions for COX6B1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIFM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKFY1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM132A Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26A Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait YIPF5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait COX6B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COX7A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM220 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in COX6B1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyt_c_oxidase_su6B IPR003213 0.01


Protein complexes (CORUM database) featuring COX6B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring COX6B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005758 mitochondrial intermembrane space Database 0.33
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Disease phenotype Leigh_syndrome_with_cardiomyopathy Leigh syndrome with cardiomyopathy Database 0.09
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Pathway Pathway_198 KEGG_CARDIAC_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Disease phenotype Isolated_cytochrome_C_oxidase_deficiency Isolated cytochrome C oxidase deficiency Database 0
Category members Disease phenotype MITOCHONDRIAL_COMPLEX_IV_DEFICIENCY MITOCHONDRIAL COMPLEX IV DEFICIENCY Database 0
Category members Disease phenotype mitochondrial_complex_IV_deficiency_(MT-C4D) mitochondrial complex IV deficiency (MT-C4D) Database 0
Category members GO Category GO:0004129 cytochrome-c oxidase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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