Results for the Category
Leigh syndrome with cardiomyopathy
(Leigh_syndrome_with_cardiomyopathy)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PDHA1 | 1 | -0.760 | 1.860 | |||||
| PDHA1 | 1 | 0.410 | -0.200 | |||||
| PDHA1 | 1 | -0.760 | 1.860 | 0.830 | -0.675 | -1.114 | 0.710 | 0.474 |
| PDHA1 | 1 | 0.410 | -0.200 | 0.830 | -0.675 | -1.114 | 0.710 | 0.474 |
| COX15 | 0 | 0.370 | -0.560 | 0.378 | 0.563 | |||
| COX6B1 | 0 | 0.040 | 0.480 | 0.423 | ||||
| SCO2 | 0 | 1.270 | -0.340 | -0.179 | 0.206 | -0.289 | -0.057 | |
| TACO1 | 0 | -0.360 | 0.200 | -0.207 | 0.648 | 0.752 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| COX6B1 | Ubiquitylation | K13 | -1.330 | 0.150 | _NYK(gl)TAPFDSR_ |
| COX6B1 | Ubiquitylation | K47 | -0.072 | _AMTAK(gl)GGDISVCEWYQR_ | |
| PDHA1 | Phosphorylation | T231 | 1.539 | 1.081 | _YGMGT(ph)SVER_ |
| PDHA1 | Phosphorylation | S232 | 1.452 | 0.823 | _YGM(ox)GTS(ph)VER_ |
| PDHA1 | Ubiquitylation | K244 | -0.931 | _AAASTDYYK(gl)R_ | |
| PDHA1 | Phosphorylation | S293 | 0.346 | 0.996 | _YHGHS(ph)M(ox)SDPGVSYR_ |
| PDHA1 | Phosphorylation | S295 | 0.274 | 0.755 | _YHGHSMS(ph)DPGVSYR_ |
| SCO2 | Ubiquitylation | K196 | -0.539 | 0.337 | _LLGLTGSTK(gl)QVAQASHSYR_ |
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