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Query: SCO2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCO2 0 -0.342 1.270 -0.340 -0.179 0.206 -0.289 -0.057

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCO2 Ubiquitylation K196 -0.539 0.337 _LLGLTGSTK(gl)QVAQASHSYR_

Background Information for SCO2:


Pubmed-SCO2 »
Uniprot-SCO2 »
Biogrid-SCO2 »
ProteomicsDB-SCO2 »

Tumorportal-SCO2 »
COSMIC-SCO2 »
GenomeRNAi-SCO2 »
Genecards-SCO2


Protein-protein Interactions for SCO2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGEA10 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015


Protein Domains in SCO2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Thioredoxin-like_fold IPR012336 0.16
Category members SCO1/SenC IPR003782 0
Category members Synth_of_cyt-c-oxidase_Sco1/2 IPR017276 0


Protein complexes (CORUM database) featuring SCO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SCO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Disease phenotype Leigh_syndrome_with_cardiomyopathy Leigh syndrome with cardiomyopathy Database 0.09
Category members GO Category GO:0006878 cellular copper ion homeostasis Database 0.04
Category members Disease phenotype CARDIOENCEPHALOMYOPATHY_FATAL_INFANTILE_DUE_TO_CYTOCHROME_c_OXIDASE CARDIOENCEPHALOMYOPATHY FATAL INFANTILE DUE TO CYTOCHROME c OXIDASE Database 0
Category members Disease phenotype Fatal_infantile_cytochrome_C_oxidase_deficiency Fatal infantile cytochrome C oxidase deficiency Database 0
Category members Disease phenotype Rare_isolated_myopia Rare isolated myopia Database 0
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0005507 copper ion binding Database 0
Category members GO Category GO:0006825 copper ion transport Database 0
Category members GO Category GO:0008535 respiratory chain complex IV assembly Database 0
Category members GO Category GO:0014823 response to activity Database 0
Category members GO Category GO:0030016 myofibril Database 0
Category members GO Category GO:0055070 copper ion homeostasis Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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