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Query: CDC42BPB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDC42BPB 0 7.350 -1.290 1.790 0.546 0.645 0.683

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDC42BPB Ubiquitylation K1337 1.400 1.105 _GCQLMATATLK(gl)R_
CDC42BPB Ubiquitylation K426 0.566 _SIMQSNTLTK(gl)DEDVQR_
CDC42BPB Phosphorylation S481 0.701 0.480 _ALSNS(ph)NRDKEIK_
CDC42BPB Ubiquitylation K338 -0.347 _LGQNGIEDFKK(gl)_
CDC42BPB Phosphorylation S1690 -1.711 -2.133 _HSTPSNSSNPSGPPS(ph)PNSPHR_

Background Information for CDC42BPB:


Pubmed-CDC42BPB »
Uniprot-CDC42BPB »
Biogrid-CDC42BPB »
ProteomicsDB-CDC42BPB »

Tumorportal-CDC42BPB »
COSMIC-CDC42BPB »
GenomeRNAi-CDC42BPB »
Genecards-CDC42BPB


Protein-protein Interactions for CDC42BPB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCZ Cat. description Hein, Mann, Cell 2015
Category members IP bait RXRB Cat. description Hein, Mann, Cell 2015
Category members IP bait TECPR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf183 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf150 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDC42BPB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members DAG/PE-bd IPR020454 0.18
Category members PH_domain IPR001849 0.14
Category members CRIB_dom IPR000095 0.13
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members AGC-kinase_C IPR000961 0
Category members Citron IPR001180 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Myotonic_dystrophy_kinase_coil IPR014930 0
Category members Pkinase_C IPR017892 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDC42BPB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDC42BPB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0042641 actomyosin Database 0.9
Category members GO Category GO:0017048 Rho GTPase binding Database 0.69
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0031032 actomyosin structure organization Database 0.15
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0005083 small GTPase regulator activity Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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