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Query: ARHGDIA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGDIA 0 -2.534 -0.150 -0.030 0.141 -2.525

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGDIA Ubiquitylation K178 0.739 _GSYSIK(gl)SR_
ARHGDIA Ubiquitylation K141 0.314 0.567 _IDK(gl)TDYM(ox)VGSYGPR_
ARHGDIA Ubiquitylation K52 0.380 _YK(gl)EALLGR_
ARHGDIA Phosphorylation S24 -1.058 -0.942 _(ac)AEQEPTAEQLAQIAAENEEDEHS(ph)VNYKPPAQK_
ARHGDIA Ubiquitylation K99 0.365 _K(gl)QSFVLK_
ARHGDIA Ubiquitylation K127 1.141 _EIVSGMK(gl)YIQHTYR_
ARHGDIA Ubiquitylation K167 -1.199 _AEEYEFLTPVEEAPK(gl)GMLAR_

Background Information for ARHGDIA:


Pubmed-ARHGDIA »
Uniprot-ARHGDIA »
Biogrid-ARHGDIA »
ProteomicsDB-ARHGDIA »

Tumorportal-ARHGDIA »
COSMIC-ARHGDIA »
GenomeRNAi-ARHGDIA »
Genecards-ARHGDIA


Protein-protein Interactions for ARHGDIA
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ARHGDIA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GDI IPR000406 0
Category members Ig_E-set IPR014756 0


Protein complexes (CORUM database) featuring ARHGDIA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARHGDIA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members Pathway Pathway_1157 PID_RAC1_REG_PATHWAY 0 0
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Disease phenotype Familial_idiopathic_steroid-resistant_nephrotic_syndrome_with_diffuse_mesangial_sclerosis Familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis Database 0
Category members GO Category GO:0001772 immunological synapse Database 0
Category members GO Category GO:0005094 Rho GDP-dissociation inhibitor activity Database 0
Category members GO Category GO:0007162 negative regulation of cell adhesion Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0032880 regulation of protein localization Database 0
Category members GO Category GO:0050770 regulation of axonogenesis Database 0
Category members GO Category GO:0050771 negative regulation of axonogenesis Database 0
Category members GO Category GO:0050772 positive regulation of axonogenesis Database 0


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