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Query: ARFGAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARFGAP1 0 2.430 0.210 -0.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARFGAP1 Phosphorylation S343 0.527 0.767 _S(ph)PSSDSWTCADTSTER_
ARFGAP1 Ubiquitylation K74 0.390 0.746 _DIELEK(gl)MK_
ARFGAP1 Phosphorylation S150 0.394 0.096 _VS(ph)GQPQSVTASSDK_
ARFGAP1 Phosphorylation S37 0.390 0.076 _VS(ph)GQPQSVTASSDK_
ARFGAP1 Phosphorylation S144 -0.169 -0.150 _TLPS(ph)M(ox)VHRVSGQPQSVTASSDK_
ARFGAP1 Ubiquitylation K231 -0.415 _EGATK(gl)FGSQASQK_
ARFGAP1 Ubiquitylation K226 -0.373 _FASAAK(gl)EGATK_

Background Information for ARFGAP1:


Pubmed-ARFGAP1 »
Uniprot-ARFGAP1 »
Biogrid-ARFGAP1 »
ProteomicsDB-ARFGAP1 »

Tumorportal-ARFGAP1 »
COSMIC-ARFGAP1 »
GenomeRNAi-ARFGAP1 »
Genecards-ARFGAP1


Protein-protein Interactions for ARFGAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARFGAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSTM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARFGAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ArfGAP IPR001164 0


Protein complexes (CORUM database) featuring ARFGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARFGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_670 PID_ARF_3PATHWAY 0 3.15
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members Pathway Pathway_709 BIOCARTA_ARAP_PATHWAY 0 0.76
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030660 Golgi-associated vesicle membrane Database 0.44
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0006890 retrograde vesicle-mediated transport, Golgi to ER Database 0.05
Category members Pathway Pathway_1272 REACTOME_COPI_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0008060 ARF GTPase activator activity Database 0
Category members GO Category GO:0032312 regulation of ARF GTPase activity Database 0
Category members GO Category GO:0048205 COPI coating of Golgi vesicle Database 0


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