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Query: AP3D1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP3D1 0 0.202 -0.770 1.000
AP3D1 0 0.202 -0.770 1.000 -3.722 0.111 0.159

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP3D1 Phosphorylation S9 0.952 _MVKGS(ph)IDR_
AP3D1 Ubiquitylation K379 0.803 0.640 _NLMEIVKK(gl)_
AP3D1 Ubiquitylation K7 0.529 0.464 _MVK(gl)GSIDR_
AP3D1 Phosphorylation S738 -0.194 -0.008 _NTETSKS(ph)PEKDVPMVEK_
AP3D1 Phosphorylation S736 -0.691 -0.892 _NTETS(ph)KSPEKDVPM(ox)VEK_
AP3D1 Phosphorylation T735 0.260 -0.981 _NTET(ph)SKSPEKDVPM(ox)VEK_

Background Information for AP3D1:


Pubmed-AP3D1 »
Uniprot-AP3D1 »
Biogrid-AP3D1 »
ProteomicsDB-AP3D1 »

Tumorportal-AP3D1 »
COSMIC-AP3D1 »
GenomeRNAi-AP3D1 »
Genecards-AP3D1


Protein-protein Interactions for AP3D1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DAP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3M2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF2C3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM63A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP3D1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Clathrin/coatomer_adapt-like_N IPR002553 0


Protein complexes (CORUM database) featuring AP3D1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 59 AP3 adapter complex Database 0.58
Category members Corum 2307 AP3D1-AP3S2 complex Database 0.24
Category members Corum 2308 AP3D1-AP3S1 complex Database 0.24
Category members Corum 652 AP3-BLOC1 complex Database 0


Categories featuring AP3D1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0048499 synaptic vesicle membrane organization Database 0.22
Category members GO Category GO:0061088 regulation of sequestering of zinc ion Database 0.13
Category members GO Category GO:0019882 antigen processing and presentation Database 0.03
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0006726 eye pigment biosynthetic process Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0030117 membrane coat Database 0
Category members GO Category GO:0033365 protein localization to organelle Database 0
Category members GO Category GO:0043195 terminal bouton Database 0
Category members GO Category GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib Database 0
Category members GO Category GO:0048490 anterograde synaptic vesicle transport Database 0
Category members GO Category GO:0051138 positive regulation of NK T cell differentiation Database 0


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