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Query: AMBRA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AMBRA1 0 -3.261 1.670 -0.450 -1.226 -2.109

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AMBRA1 Ubiquitylation K175 -0.373 0.447 _REPFAVVK(gl)TASEMER_

Background Information for AMBRA1:


Pubmed-AMBRA1 »
Uniprot-AMBRA1 »
Biogrid-AMBRA1 »
ProteomicsDB-AMBRA1 »

Tumorportal-AMBRA1 »
COSMIC-AMBRA1 »
GenomeRNAi-AMBRA1 »
Genecards-AMBRA1


Protein-protein Interactions for AMBRA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMBRA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CISH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFPL4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOCS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AMBRA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring AMBRA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AMBRA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0005776 autophagic vacuole Database 0
Category members GO Category GO:0005930 axoneme Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0


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