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Query: AKAP13

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKAP13 1 3.067 -0.260 0.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKAP13 Phosphorylation S2721 1.298 1.110 _S(ph)GSLDSELSVSPK_
AKAP13 Phosphorylation S1650 1.957 1.098 _VDSLVSLS(ph)EEDLESDQR_
AKAP13 Phosphorylation S2564 0.644 0.859 _S(ph)LSRPSSLIEQEK_
AKAP13 Phosphorylation S1645 0.260 0.639 _VDS(ph)LVSLSEEDLESDQR_
AKAP13 Phosphorylation S1932 0.162 0.318 _FLSHS(ph)TDSLNK_
AKAP13 Phosphorylation S2566 0.600 0.289 _SLS(ph)RPSSLIEQEK_
AKAP13 Phosphorylation S2731 -0.105 0.196 _SGSLDSELSVS(ph)PK_
AKAP13 Phosphorylation S1407 0.033 _ENWCTIEPCPDAASLLAS(ph)KQSPECENFLDVGLGR_
AKAP13 Phosphorylation S2401 -0.038 _DMAECSTPLPEDCS(ph)PTHSPR_
AKAP13 Phosphorylation S1879 -0.267 -0.048 _S(ph)AVLLVDETATTPIFANR_
AKAP13 Phosphorylation S2712 -1.063 _IPSFFPSPEEPPS(ph)PSAPSIAK_

Background Information for AKAP13:


Pubmed-AKAP13 »
Uniprot-AKAP13 »
Biogrid-AKAP13 »
ProteomicsDB-AKAP13 »

Tumorportal-AKAP13 »
COSMIC-AKAP13 »
GenomeRNAi-AKAP13 »
Genecards-AKAP13


Protein-protein Interactions for AKAP13
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APC Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKAR2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AKAP13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members PH_domain IPR001849 0.14
Category members RII_binding_1 IPR018459 0.12
Category members DH-domain IPR000219 0.05
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring AKAP13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AKAP13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0032947 protein complex scaffold Database 0.82
Category members GO Category GO:0017048 Rho GTPase binding Database 0.69
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members Pathway Pathway_1099 BIOCARTA_AKAP13_PATHWAY 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0004691 cAMP-dependent protein kinase activity Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0010611 regulation of cardiac muscle hypertrophy Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051018 protein kinase A binding Database 0
Category members GO Category GO:0051168 nuclear export Database 0


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