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Query: ACTL6A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACTL6A 0 -0.515 1.180 -1.200 -0.232 -0.204 0.672 -0.015 0.126

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACTL6A Phosphorylation S233 0.000 _EGS(ph)PANWK_
ACTL6A Ubiquitylation K379 0.076 -0.470 _LK(gl)LIANNTTVER_
ACTL6A Ubiquitylation K238 -0.635 _EGSPANWK(gl)R_
ACTL6A Ubiquitylation K242 -0.676 _EK(gl)LPQVTR_
ACTL6A Ubiquitylation K371 -0.788 _ELSQK(gl)TPPSMR_

Background Information for ACTL6A:


Pubmed-ACTL6A »
Uniprot-ACTL6A »
Biogrid-ACTL6A »
ProteomicsDB-ACTL6A »

Tumorportal-ACTL6A »
COSMIC-ACTL6A »
GenomeRNAi-ACTL6A »
Genecards-ACTL6A


Protein-protein Interactions for ACTL6A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7C Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMARCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTL6A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SS18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRANB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACTL6A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Actin-related IPR004000 0.11


Protein complexes (CORUM database) featuring ACTL6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 778 LARC complex (LCR-associated remodeling complex) Database 5.04
Category members Corum 739 SIN3-ING1b complex II Database 4.24
Category members Corum 714 BRM-SIN3A complex Database 4.02
Category members Corum 1230 WINAC complex Database 3.79
Category members Corum 713 BRG1-SIN3A complex Database 3.51
Category members Corum 1252 EBAFa complex Database 2.5
Category members Corum 806 BRM-SIN3A-HDAC complex Database 2.48
Category members Corum 1237 BAF complex Database 2.03
Category members Corum 555 BAF complex Database 2.03
Category members Corum 564 BAF complex Database 2.03
Category members Corum 803 BRG1-SIN3A-HDAC containing SWI/SNF remodeling complex I Database 2.01
Category members Corum 1239 EBAFb complex Database 1.57
Category members Corum 1251 BAF complex Database 1.57
Category members Corum 238 SWI-SNF chromatin remodeling-related-BRCA1 complex Database 1.57
Category members Corum 554 PBAF complex (Polybromo- and BAF containing complex) Database 1.57
Category members Corum 565 PBAF complex (Polybromo- and BAF containing complex) Database 1.57
Category members Corum 566 BAF complex Database 1.57
Category members Corum 710 Brg1-associated complex I Database 1.57
Category members Corum 711 Brm-associated complex Database 1.57
Category members Corum 808 BRM-associated complex Database 1.57
Category members Corum 3065 RNA polymerase II complex, chromatin structure modifying Database 1.26
Category members Corum 1238 PBAF complex (Polybromo- and BAF containing complex) Database 1.16
Category members Corum 556 PBAF complex (Polybromo- and BAF containing complex) Database 1.16
Category members Corum 807 BRG1-associated complex Database 1.16
Category members Corum 525 TIP60 histone acetylase complex Database 0.62
Category members Corum 3063 Brg1-associated complex II Database 0.62
Category members Corum 2857 NuA4/Tip60 HAT complex Database 0.28
Category members Corum 798 NuA4/Tip60-HAT complex A Database 0.28
Category members Corum 2852 Brg1-based SWI/SNF chromatin remodeling complex Database 0.23
Category members Corum 787 NuA4/Tip60-HAT complex B Database 0.23
Category members Corum 1170 cMYC-ATPase-helicase complex Database 0.16
Category members Corum 1171 c-MYC-ATPase-helicase complex Database 0.16
Category members Corum 302 INO80 chromatin remodeling complex Database 0.14
Category members Corum 1173 TIP49-TIP48-BAF53 complex Database 0.13
Category members Corum 2856 NuA4/Tip60 HAT complex Database 0.13
Category members Corum 528 NuA4/Tip60 HAT complex Database 0.07
Category members Corum 799 DMAP1-associated complex Database 0.05
Category members Corum 529 NuA4/Tip60 HAT complex Database 0.04
Category members Corum 1175 TRRAP-BAF53-HAT complex Database 0
Category members Corum 304 SRCAP-associated chromatin remodeling complex Database 0


Categories featuring ACTL6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016514 SWI/SNF complex Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0031011 Ino80 complex Database 0.29
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_858 PID_MYC_PATHWAY 0 0.17
Category members GO Category GO:0035267 NuA4 histone acetyltransferase complex Database 0.07
Category members GO Category GO:0043968 histone H2A acetylation Database 0.02
Category members GO Category GO:0003407 neural retina development Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0043967 histone H4 acetylation Database 0


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