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Results for the Category
REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1
(Pathway_271)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ITPR3 2 -0.190 -0.500 1.489 1.835
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
PRKAR2B 0 -0.290 0.380
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
GNB1 0 -0.700 0.650 0.713 0.504 0.538
GNB3 0 -1.020 1.280 0.713 0.504 0.538
GNAS 0 0.840 -0.750
GNAS 0 0.840 -0.750
GNAS 0 0.840 -0.750 -0.166 -0.094 0.032 0.420 0.504
PRKAR2A 0 -0.530 1.080 0.026 -1.317 -0.866 0.783 0.007
PRKAR2A 0 -0.530 1.080
GNB4 0 0.410 -0.240 0.137 0.627 1.296
GNB4 0 0.410 -0.240
ITPR2 0 -1.020 0.610 0.952 0.981
RAP1B 0 -0.520 0.540 -0.200 0.374 0.556
IQGAP1 0 -0.420 0.300 0.641 -0.402
IQGAP1 0 -0.420 0.300 1.363 0.406 0.007
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
GNG4 0 0.310 -0.680
GNB2 0 0.120 -0.090 0.137 0.627 1.296
GNG12 0 1.160 -1.150 -1.317
GNG12 0 1.160 -1.150
GNG5 0 -0.100 -0.480
ADCY6 0 -0.720 0.740

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADCY6 Phosphorylation S54 -1.434 -1.374 _DAEPPS(ph)PTPAGPPR_
ADCY6 Ubiquitylation K80 0.473 0.937 _GK(gl)ELGLR_
ADCY6 Ubiquitylation K568 1.007 0.799 _AMLAK(gl)LQR_
ADCY6 Phosphorylation S576 -0.020 _ANS(ph)MEGLMPR_
GNAS Ubiquitylation K8 0.430 0.328 _GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS Ubiquitylation K17 -0.011 _GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS Ubiquitylation K32 0.249 -0.446 _QLQK(gl)DKQVYR_
GNAS Ubiquitylation K58 -1.182 0.161 _STIVK(gl)QM(ox)R_
GNAS Ubiquitylation K92 -1.333 -0.290 _ATK(gl)VQDIKNNLK_
GNAS Ubiquitylation K97 0.076 _VQDIK(gl)NNLK_
GNAS Ubiquitylation K167 -1.721 _LHALK(gl)LR_
GNAS Ubiquitylation K301 -0.955 -0.198 _QDLLAEK(gl)VLAGK_
GNAS Ubiquitylation K308 -0.472 _SK(gl)IEDYFPEFAR_
GNB1 Ubiquitylation K23 -0.282 _K(gl)ACADATLSQITNNIDPVGR_
GNB1 Ubiquitylation K209 -0.296 -0.249 _LFVSGACDASAK(gl)LWDVR_
GNB2 Ubiquitylation K23 -0.095 0.033 _K(gl)ACGDSTLTQITAGLDPVGR_
GNB2 Ubiquitylation K209 0.251 0.419 _TFVSGACDASIK(gl)LWDVR_
GNB3 Ubiquitylation K23 -0.282 _K(gl)ACADATLSQITNNIDPVGR_
GNB3 Ubiquitylation K209 -0.296 -0.249 _LFVSGACDASAK(gl)LWDVR_
GNB4 Ubiquitylation K23 -0.095 0.033 _K(gl)ACGDSTLTQITAGLDPVGR_
GNB4 Ubiquitylation K23 -0.030 _K(gl)ACNDATLVQITSNMDSVGR_
GNB4 Ubiquitylation K209 0.251 0.419 _TFVSGACDASIK(gl)LWDVR_
GNB4 Ubiquitylation K209 0.019 _TFVSGACDASSK(gl)LWDIR_
GNG12 Ubiquitylation K4 0.230 0.493 _(ac)SSK(gl)TASTNNIAQAR_
GNG12 Ubiquitylation K34 0.515 1.067 _VSK(gl)ASADLMSYCEEHAR_
GNG4 Ubiquitylation K24 1.031 0.205 _KAVEQLK(gl)MEACMDR_
GNG5 Ubiquitylation K11 -0.523 0.125 _(ac)SGSSSVAAMK(gl)K_
GNG5 Ubiquitylation K12 0.232 0.466 _K(gl)VVQQLR_
GNG5 Ubiquitylation K27 -0.760 0.148 _VK(gl)VSQAAADLK_
IQGAP1 Ubiquitylation K953 0.650 _NKEQLSDMMMINK(gl)QK_
IQGAP1 Ubiquitylation K959 0.713 0.074 _GGLK(gl)ALSK_
IQGAP1 Ubiquitylation K1389 0.638 1.119 _TILLNTK(gl)R_
IQGAP1 Ubiquitylation K1442 0.488 _SK(gl)SVKEDSNLTLQEK_
IQGAP1 Phosphorylation S1443 0.392 0.273 _SKS(ph)VKEDSNLTLQEK_
IQGAP1 Ubiquitylation K1445 0.863 _SVK(gl)EDSNLTLQEK_
ITPR2 Ubiquitylation K909 -0.247 _LSK(gl)FQDGGNNVMR_
ITPR2 Phosphorylation S1160 0.443 0.895 _GGEEPIEESNILS(ph)PVQDGTK_
ITPR3 Ubiquitylation K529 1.377 _EK(gl)GGEGPLVR_
ITPR3 Phosphorylation S934 0.318 -0.802 _KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3 Phosphorylation S937 -0.026 _KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3 Ubiquitylation K1534 -0.220 _TLAMVAK(gl)GR_
ITPR3 Phosphorylation S1832 0.650 0.560 _VAS(ph)FSIPGSSSR_
ITPR3 Ubiquitylation K2597 -0.819 _NK(gl)NLDWFPR_
ITPR3 Ubiquitylation K2628 -0.010 _ILQDK(gl)LNSTMK_
ITPR3 Phosphorylation S2670 1.132 1.555 _LGFVDVQNCIS(ph)R_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR2A Phosphorylation S99 0.020 0.056 _RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A Phosphorylation T104 -0.175 _RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKAR2B Phosphorylation T69 -0.367 _TWGDLGAAAGGGT(ph)PSK_
PRKAR2B Phosphorylation S114 0.366 0.525 _RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
RAP1B Ubiquitylation K174 0.197 _KTPVPGK(gl)AR_


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