Results for the Category
REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION
(Pathway_179)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| DHPS | 0 | 0.420 | 0.020 | |||||
| GGCX | 0 | -1.340 | 2.190 | 0.587 | 0.168 | |||
| EIF5A | 0 | 1.030 | -0.800 | -0.044 | 1.340 | -1.175 | 0.031 | 0.025 |
| EIF5A | 0 | 1.250 | -0.860 | -0.044 | 1.340 | -1.175 | 0.031 | 0.025 |
| FURIN | 0 | 1.280 | -0.730 | |||||
| EIF5A2 | 0 | -0.580 | 0.130 | -0.044 | 1.340 | -1.175 | 0.031 | 0.025 |
| VKORC1 | 0 | -0.240 | -0.300 | 0.569 | 0.417 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DHPS | Ubiquitylation | K73 | -0.176 | _AVQQVNAMIEKK(gl)_ | |
| DHPS | Ubiquitylation | K205 | -0.501 | _WTPSK(gl)MIAR_ | |
| DHPS | Ubiquitylation | K366 | 1.166 | 0.058 | _MDAFMHEK(gl)NED_ |
| EIF5A | Phosphorylation | T9 | -0.003 | 0.305 | _ADDLDFET(ph)GDAGASATFPM(ox)QCSALR_ |
| EIF5A | Ubiquitylation | K27 | -0.023 | -0.373 | _K(gl)NGFVVLK_ |
| EIF5A | Ubiquitylation | K34 | -0.015 | -0.550 | _NGFVVLK(gl)GRPCK_ |
| EIF5A | Ubiquitylation | K39 | 1.330 | 0.690 | _GRPCK(gl)IVEM(ox)STSK_ |
| EIF5A | Ubiquitylation | K67 | 0.127 | _VHLVGIDIFTGK(gl)K_ | |
| EIF5A | Ubiquitylation | K68 | 0.088 | _VHLVGIDIFTGKK(gl)_ | |
| EIF5A | Ubiquitylation | K85 | -0.842 | -0.793 | _YEDICPSTHNMDVPNIK(gl)R_ |
| EIF5A | Ubiquitylation | K121 | -0.654 | _EDLRLPEGDLGK(gl)EIEQK_ | |
| EIF5A2 | Phosphorylation | T9 | -0.003 | 0.305 | _ADDLDFET(ph)GDAGASATFPM(ox)QCSALR_ |
| EIF5A2 | Ubiquitylation | K27 | -0.023 | -0.373 | _K(gl)NGFVVLK_ |
| EIF5A2 | Ubiquitylation | K34 | -0.015 | -0.550 | _NGFVVLK(gl)GRPCK_ |
| EIF5A2 | Ubiquitylation | K39 | 1.330 | 0.690 | _GRPCK(gl)IVEM(ox)STSK_ |
| EIF5A2 | Ubiquitylation | K67 | 0.127 | _VHLVGIDIFTGK(gl)K_ | |
| EIF5A2 | Ubiquitylation | K68 | 0.088 | _VHLVGIDIFTGKK(gl)_ | |
| EIF5A2 | Ubiquitylation | K85 | -0.842 | -0.793 | _YEDICPSTHNMDVPNIK(gl)R_ |
| EIF5A2 | Ubiquitylation | K121 | -0.654 | _EDLRLPEGDLGK(gl)EIEQK_ | |
| FURIN | Ubiquitylation | K789 | -1.074 | -0.470 | _TAFIK(gl)DQSAL_ |
| GGCX | Ubiquitylation | K19 | -0.003 | _TSPSSDKVQK(gl)DKAELISGPR_ | |
| GGCX | Ubiquitylation | K21 | -0.057 | 0.561 | _DK(gl)AELISGPR_ |
| GGCX | Ubiquitylation | K334 | -0.772 | _LQQLLPLK(gl)AAPQPSVSCVYK_ | |
| GGCX | Ubiquitylation | K346 | 0.136 | _AAPQPSVSCVYK(gl)R_ | |
| GGCX | Ubiquitylation | K515 | 0.140 | _AK(gl)LQEIK_ |
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