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Query: DHPS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHPS 0 1.225 0.420 0.020

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHPS Ubiquitylation K366 1.166 0.058 _MDAFMHEK(gl)NED_
DHPS Ubiquitylation K73 -0.176 _AVQQVNAMIEKK(gl)_
DHPS Ubiquitylation K205 -0.501 _WTPSK(gl)MIAR_

Background Information for DHPS:


Pubmed-DHPS »
Uniprot-DHPS »
Biogrid-DHPS »
ProteomicsDB-DHPS »

Tumorportal-DHPS »
COSMIC-DHPS »
GenomeRNAi-DHPS »
Genecards-DHPS


Protein-protein Interactions for DHPS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGAP15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BYSL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf93 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNAB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAFB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFPQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPHK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIRAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF414 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHPS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DHS-like_NAD/FAD-binding_dom IPR029035 0


Protein complexes (CORUM database) featuring DHPS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHPS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members Pathway Pathway_179 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 0 0.06
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0008612 peptidyl-lysine modification to hypusine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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