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Query: GGCX

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GGCX 0 3.503 -1.340 2.190 0.587 0.168

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GGCX Ubiquitylation K21 -0.057 0.561 _DK(gl)AELISGPR_
GGCX Ubiquitylation K515 0.140 _AK(gl)LQEIK_
GGCX Ubiquitylation K346 0.136 _AAPQPSVSCVYK(gl)R_
GGCX Ubiquitylation K334 -0.772 _LQQLLPLK(gl)AAPQPSVSCVYK_
GGCX Ubiquitylation K19 -0.003 _TSPSSDKVQK(gl)DKAELISGPR_

Background Information for GGCX:


Pubmed-GGCX »
Uniprot-GGCX »
Biogrid-GGCX »
ProteomicsDB-GGCX »

Tumorportal-GGCX »
COSMIC-GGCX »
GenomeRNAi-GGCX »
Genecards-GGCX


Protein-protein Interactions for GGCX
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP1S2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM46A Cat. description Hein, Mann, Cell 2015
Category members IP bait FGD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TERF2IP Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMCO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GGCX
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RmlC_Cupin IPR011051 0


Protein complexes (CORUM database) featuring GGCX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GGCX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0017187 peptidyl-glutamic acid carboxylation Database 0.13
Category members Pathway Pathway_179 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 0 0.06
Category members Pathway Pathway_1239 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS 0 0.06
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Disease phenotype Hereditary_combined_deficiency_of_vitamin_K-dependent_clotting_factors Hereditary combined deficiency of vitamin K-dependent clotting factors Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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