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Query: VKORC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VKORC1 0 0.986 -0.240 -0.300 0.569 0.417

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for VKORC1:


Pubmed-VKORC1 »
Uniprot-VKORC1 »
Biogrid-VKORC1 »
ProteomicsDB-VKORC1 »

Tumorportal-VKORC1 »
COSMIC-VKORC1 »
GenomeRNAi-VKORC1 »
Genecards-VKORC1


Protein-protein Interactions for VKORC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PABPC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VKORC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members VKOR IPR012932 0


Protein complexes (CORUM database) featuring VKORC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VKORC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0017187 peptidyl-glutamic acid carboxylation Database 0.13
Category members Pathway Pathway_179 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 0 0.06
Category members Pathway Pathway_1239 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS 0 0.06
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Disease phenotype Hereditary_combined_deficiency_of_vitamin_K-dependent_clotting_factors Hereditary combined deficiency of vitamin K-dependent clotting factors Database 0
Category members GO Category GO:0017144 drug metabolic process Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0047057 vitamin-K-epoxide reductase (warfarin-sensitive) activity Database 0


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