RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
MAPK3	0
STAT1	0	-0.550	0.170
ADAM17	0	0.520	-0.620
STAT3	0	0.200	-1.270					0.334
IRS1	0
STAT5B	0	0.670	-0.960
SH2B1	0	0.970	0.010
IRS2	0	-0.190	-0.130
PTPN1	0	-0.150	0.310	1.066	0.459	0.251	0.322	0.379

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ADAM17	Phosphorylation	S791	-0.594	0.152	_S(ph)FEDLTDHPVTR_
IRS1	Phosphorylation	S1101	-0.078		_HSS(ph)ETFSSTPSATR_
IRS2	Phosphorylation	S308	-0.079	-0.510	_SKS(ph)QSSGSSATHPISVPGAR_
IRS2	Phosphorylation	T365	0.641	0.852	_T(ph)ASEGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S367	0.757	0.612	_TAS(ph)EGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S393	-1.580	-1.221	_PVSVAGSPLS(ph)PGPVR_
IRS2	Phosphorylation	S520	0.359	-1.006	_S(ph)NTPESIAETPPAR_
IRS2	Phosphorylation	T522	-1.103	-0.770	_SNT(ph)PESIAETPPAR_
IRS2	Phosphorylation	T529	0.230	0.164	_S(ph)NTPESIAET(ph)PPAR_
IRS2	Phosphorylation	S562	-0.026	0.439	_RVS(ph)GDAAQDLDR_
IRS2	Phosphorylation	S579	0.542	0.362	_RTYS(ph)LTTPAR_
IRS2	Phosphorylation	S621		-0.190	_LCPSCPAS(ph)SPK_
IRS2	Phosphorylation	S622	-0.195		_LCPSCPASS(ph)PK_
IRS2	Phosphorylation	S681	0.409		_SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2	Phosphorylation	S732	-1.089		_AS(ph)SPAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S733	-1.027	0.522	_ASS(ph)PAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S738		0.522	_ASS(ph)PAESS(ph)PEDSGYMR_
IRS2	Phosphorylation	S917	-0.592	-1.025	_S(ph)PGEYINIDFGEPGAR_
IRS2	Phosphorylation	S1164		-0.499	_HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2	Phosphorylation	S1178	0.766	0.277	_HNSAS(ph)VENVSLR_
IRS2	Phosphorylation	T1204		-0.454	_SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2	Phosphorylation	S1205	-0.291		_SSEGGVGVGPGGGDEPPTS(ph)PR_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
PTPN1	Phosphorylation	S352		0.032	_GS(ph)PLNAAPYGIESMSQDTEVR_
PTPN1	Phosphorylation	S365	-0.247	0.956	_GSPLNAAPYGIESMS(ph)QDTEVR_
PTPN1	Phosphorylation	S378	1.462	1.262	_VVGGS(ph)LR_
SH2B1	Phosphorylation	S96	0.112	-0.143	_ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR_
SH2B1	Phosphorylation	S125	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SH2B1	Phosphorylation	S126	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B	Phosphorylation	S194		0.270	_IQAQFGPLAQLS(ph)PQER_