Results for the Category
negative regulation of retinoic acid receptor signaling pathway
(GO:0048387)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| EZH2 | 0 | 1.100 | -0.960 | 0.524 | 0.464 | -0.045 | ||
| CNOT1 | 0 | 0.579 | -0.249 | -0.264 | -0.019 | |||
| ASXL1 | 0 | -0.670 | 0.740 | -1.339 | ||||
| CALR | 0 | -1.300 | 2.220 | 0.480 | 0.054 | |||
| PRAME | 0 | -0.110 | -0.120 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ASXL1 | Ubiquitylation | K351 | 0.813 | 0.619 | _KVEQWK(gl)EK_ |
| ASXL1 | Ubiquitylation | K353 | 0.339 | _KVEQWK(gl)EK_ | |
| ASXL1 | Phosphorylation | S501 | -0.370 | _AS(ph)ASPDRIPSLPQETVDQEPK_ | |
| ASXL1 | Phosphorylation | S503 | -0.013 | -0.206 | _ASAS(ph)PDRIPSLPQETVDQEPK_ |
| CALR | Ubiquitylation | K48 | 0.703 | _SDFGK(gl)FVLSSGK_ | |
| CALR | Ubiquitylation | K153 | -0.924 | 0.619 | _GK(gl)NVLINK_ |
| CALR | Ubiquitylation | K159 | -1.004 | 0.381 | _NVLINK(gl)DIR_ |
| CNOT1 | Phosphorylation | S1061 | 0.555 | 0.326 | _TVTVTRPTGVS(ph)FKK_ |
| CNOT1 | Ubiquitylation | K1064 | -0.495 | _TVTVTRPTGVSFKK(gl)_ | |
| CNOT1 | Ubiquitylation | K1708 | 0.686 | _AYGSPWCNK(gl)QITR_ | |
| CNOT1 | Ubiquitylation | K2185 | -0.010 | 0.228 | _DLDSYLK(gl)TR_ |
| EZH2 | Ubiquitylation | K61 | 0.548 | _TEILNQEWK(gl)QR_ | |
| EZH2 | Phosphorylation | S363 | 0.010 | -0.733 | _GRLPNNSS(ph)RPSTPTINVLESK_ |
| EZH2 | Phosphorylation | S366 | -0.266 | -0.699 | _GRLPNNSSRPS(ph)TPTINVLESK_ |
| EZH2 | Phosphorylation | T367 | 0.320 | -0.372 | _LPNNSSRPST(ph)PTINVLESK_ |
| EZH2 | Phosphorylation | T369 | -0.911 | _GRLPNNSSRPSTPT(ph)INVLESK_ | |
| EZH2 | Phosphorylation | T487 | -0.501 | -0.532 | _VKESSIIAPAPAEDVDT(ph)PPR_ |
| EZH2 | Ubiquitylation | K569 | -0.974 | _AQCNTK(gl)QCPCYLAVR_ | |
| EZH2 | Ubiquitylation | K713 | -0.461 | _IGIFAK(gl)R_ | |
| EZH2 | Ubiquitylation | K735 | 0.038 | _YSQADALK(gl)YVGIER_ | |
| PRAME | Ubiquitylation | K157 | -2.418 | _ASLYSFPEPEAAQPMTK(gl)K_ | |
| PRAME | Ubiquitylation | K158 | -2.418 | _ASLYSFPEPEAAQPMTK(gl)K_ |
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