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Query: PRAME

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRAME 0 -2.418 -0.110 -0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRAME Ubiquitylation K157 -2.418 _ASLYSFPEPEAAQPMTK(gl)K_
PRAME Ubiquitylation K158 -2.418 _ASLYSFPEPEAAQPMTK(gl)K_

Background Information for PRAME:


Pubmed-PRAME »
Uniprot-PRAME »
Biogrid-PRAME »
ProteomicsDB-PRAME »

Tumorportal-PRAME »
COSMIC-PRAME »
GenomeRNAi-PRAME »
Genecards-PRAME


Protein-protein Interactions for PRAME
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DAAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FSCN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT81 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPY2R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRAME Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QTRT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF562 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRAME
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PRAME
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRAME
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0042974 retinoic acid receptor binding Database 0.02
Category members GO Category GO:0048387 negative regulation of retinoic acid receptor signaling pathway Database 0.01
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0045596 negative regulation of cell differentiation Database 0


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