RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
SHMT1	1	-0.120	0.930
SHMT1	1	-0.120	0.930	0.878	1.600	-2.560	0.964	0.784
SHMT2	1	-0.540	1.300	0.878	1.600	-2.560	0.964	0.784
MTHFD1	0	-0.470	0.110		0.477
MTHFD1	0	-0.470	0.110	0.256			0.731	0.774
MTHFD1L	0	0.490	0.280	0.113	-0.190	-0.816	-0.058	0.299
MTHFR	0	-0.450	0.210	-0.418

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
MTHFD1	Ubiquitylation	K114	0.313		_LK(gl)AAEEIGIK_
MTHFD1	Ubiquitylation	K644	0.727	0.588	_LGK(gl)MVVASSK_
MTHFD1	Ubiquitylation	K740		0.576	_FFNIK(gl)CR_
MTHFD1	Ubiquitylation	K795		-0.151	_GFSNLK(gl)K_
MTHFD1	Ubiquitylation	K910	-0.200		_AEVYTK(gl)QGFGNLPICMAK_
MTHFD1L	Phosphorylation	S358	-0.683	-0.630	_LQPLS(ph)PVPSDIEISR_
SHMT1	Ubiquitylation	K72		-0.735	_AVLEALGSCLNNK(gl)YSEGYPGQR_
SHMT1	Ubiquitylation	K103	-2.726	-0.554	_YSEGYPGK(gl)R_
SHMT1	Ubiquitylation	K280		-0.564	_HADIVTTTTHK(gl)TLR_
SHMT1	Ubiquitylation	K356		1.096	_EYSLQVLK(gl)NAR_
SHMT1	Ubiquitylation	K386		-0.881	_VLEACSIACNK(gl)NTCPGDR_
SHMT1	Ubiquitylation	K409		0.692	_VLELVSITANK(gl)NTCPGDR_
SHMT1	Ubiquitylation	K416	-0.549	-0.533	_GLLEK(gl)DFQK_
SHMT1	Ubiquitylation	K446		-1.125	_ATLK(gl)EFK_
SHMT1	Ubiquitylation	K469		-0.436	_LQDFK(gl)SFLLK_
SHMT1	Ubiquitylation	K474	-1.113	-0.594	_SFLLK(gl)DSETSQR_
SHMT2	Ubiquitylation	K103	-2.726	-0.554	_YSEGYPGK(gl)R_
SHMT2	Ubiquitylation	K280		-0.564	_HADIVTTTTHK(gl)TLR_
SHMT2	Ubiquitylation	K356		1.096	_EYSLQVLK(gl)NAR_
SHMT2	Ubiquitylation	K409		0.692	_VLELVSITANK(gl)NTCPGDR_
SHMT2	Ubiquitylation	K469		-0.436	_LQDFK(gl)SFLLK_
SHMT2	Ubiquitylation	K474	-1.113	-0.594	_SFLLK(gl)DSETSQR_