Results for the Category
regulation of transforming growth factor beta receptor signaling pathway
(GO:0017015)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| TRIM33 | 1 | -1.430 | 2.720 | -0.662 | -0.190 | 0.683 | 0.034 | 0.316 |
| TGFB1 | 0 | -0.550 | 1.050 | |||||
| SMAD4 | 0 | 0.420 | -0.390 | 0.020 | 0.556 | -0.485 | ||
| ZEB1 | 0 | 0.640 | -0.450 | |||||
| ZEB1 | 0 | 0.640 | -0.450 | |||||
| SMAD3 | 0 | -1.560 | 1.800 | |||||
| SMAD3 | 0 | 0.270 | -0.340 | |||||
| SMAD2 | 0 | |||||||
| EID2 | 0 | -1.000 | 1.160 | |||||
| ZNF703 | 0 | 0.510 | -0.810 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| EID2 | Phosphorylation | S94 | -0.850 | _AAAAGRES(ph)PAAAAAR_ | |
| SMAD2 | Phosphorylation | T8 | -0.896 | -0.885 | _(ac)SSILPFT(ph)PPVVK_ |
| SMAD2 | Ubiquitylation | K13 | -0.058 | _(ac)SSILPFTPPVVK(gl)R_ | |
| SMAD3 | Ubiquitylation | K13 | -0.704 | _(ac)SSILPFTPPIVK(gl)R_ | |
| TGFB1 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ | |
| TRIM33 | Ubiquitylation | K356 | 0.156 | _IKEVNETNK(gl)R_ | |
| TRIM33 | Ubiquitylation | K769 | 0.051 | _TSLSFK(gl)SDQVK_ | |
| ZEB1 | Ubiquitylation | K77 | 0.237 | _FTSLK(gl)EHIK_ | |
| ZEB1 | Ubiquitylation | K398 | -0.697 | 0.131 | _SEK(gl)LPEDLTVK_ |
| ZEB1 | Phosphorylation | S713 | -0.669 | -0.753 | _NNDQPQSANANEPQDSTVNLQS(ph)PLK_ |
| ZEB1 | Phosphorylation | S1025 | 0.260 | _REAEERDS(ph)TEQEEAGPEILSNEHVGAR_ | |
| ZEB1 | Phosphorylation | T1026 | 0.260 | _REAEERDS(ph)TEQEEAGPEILSNEHVGAR_ | |
| ZNF703 | Phosphorylation | S2 | -0.222 | _(ac)S(ph)DSPAGS(ph)NPRTPESSGSGSGGGGK_ | |
| ZNF703 | Phosphorylation | S8 | -0.222 | _(ac)S(ph)DSPAGS(ph)NPRTPESSGSGSGGGGK_ | |
| ZNF703 | Phosphorylation | T12 | -0.699 | 0.126 | _(ac)SDSPAGSNPRT(ph)PESSGSGSGGGGK_ |
| ZNF703 | Phosphorylation | S252 | -0.792 | -0.340 | _DQEPKPS(ph)PEPAAVSR_ |
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