Results for the Category
Familial pancreatic carcinoma
(Familial_pancreatic_carcinoma)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
BRCA1 | 2 | 0.200 | -0.140 | 0.433 | 0.018 | 0.146 | ||
PALB2 | 1 | -1.420 | 3.110 | |||||
KRAS | 1 | -0.510 | 0.620 | 1.031 | 0.887 | |||
KRAS | 1 | -0.510 | 0.620 | 0.246 | -0.346 | |||
TP53 | 0 | -1.070 | 1.050 | -2.808 | 0.076 | -0.094 | 0.436 | 0.497 |
SMAD4 | 0 | 0.420 | -0.390 | 0.020 | 0.556 | -0.485 | ||
CDKN2A | 0 | -0.080 | -0.260 | -0.556 | -1.080 | -3.270 | -1.110 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
BRCA1 | Phosphorylation | S123 | 0.465 | 0.445 | _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_ |
BRCA1 | Phosphorylation | S753 | 2.662 | 4.077 | _VSNNAEDPKDLMLS(ph)GER_ |
BRCA1 | Phosphorylation | S1009 | 0.733 | 1.028 | _KNLLEENFEEHSM(ox)S(ph)PER_ |
BRCA1 | Phosphorylation | S1546 | 1.821 | 2.105 | _NYPS(ph)QEELIK_ |
BRCA1 | Phosphorylation | S1564 | 3.065 | _VVDVEEQQLEES(ph)GPHDLTETSYLPR_ | |
BRCA1 | Phosphorylation | S1664 | 1.120 | _EKPELTAS(ph)TER_ | |
KRAS | Ubiquitylation | K128 | 1.528 | 1.433 | _TVDTK(gl)QAHELAK_ |
KRAS | Ubiquitylation | K235 | 0.591 | 0.087 | _TVDTK(gl)QAQDLAR_ |
KRAS | Ubiquitylation | K254 | -0.450 | -0.156 | _SYGIPFIETSAK(gl)TR_ |
PALB2 | Phosphorylation | S190 | 1.462 | 1.104 | _NPARS(ph)PVTEIR_ |
PALB2 | Phosphorylation | S387 | -1.951 | _SLS(ph)LEATS(ph)PLSAEK_ | |
PALB2 | Phosphorylation | S660 | 0.033 | -0.373 | _EGSCIFPEELS(ph)PK_ |
TP53 | Ubiquitylation | K120 | -0.188 | _LGFLHSGTAK(gl)SVTCTYSPALNK_ | |
TP53 | Ubiquitylation | K164 | 0.157 | -1.260 | _AMAIYK(gl)QSQHMTEVVR_ |
TP53 | Phosphorylation | S314 | -0.695 | -1.000 | _ALPNNTSS(ph)SPQPK_ |
TP53 | Phosphorylation | S315 | -0.762 | -0.959 | _RALPNNTSSS(ph)PQPK_ |
TP53 | Ubiquitylation | K320 | -0.978 | _ALPNNTSSSPQPKK(gl)_ | |
TP53 | Ubiquitylation | K357 | -0.231 | -0.823 | _ELNEALELKDAQAGK(gl)EPGGSR_ |
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