RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
EXOSC3	1	-1.840	3.020	-0.152	-0.472	-0.227	-0.542	-0.121
EXOSC8	1	-2.330	4.300	0.175
EXOSC7	0	0.320	0.360	0.498	-0.198	0.040	0.896	-0.129
EXOSC5	0	-1.260	2.170
EXOSC5	0	-1.260	2.170				0.148	0.414
DIS3	0	0.150	-0.690
DIS3	0	0.150	-0.690	-0.335			-0.438	-0.111
EXOSC9	0			0.080	0.519	0.128	-0.495	0.107
EXOSC2	0	-0.410	0.130	-0.167	0.162	0.416	-0.803	0.148
EXOSC1	0	-1.320	2.040	-0.540			-0.773	-0.524
EXOSC10	0	0.160	-0.170		-0.327	-0.108	-0.734	-0.003
EXOSC6	0	1.090	-0.810	-0.397			-1.242	-0.177

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
DIS3	Ubiquitylation	K337	-0.491		_TAVSEK(gl)MLKPTGR_
DIS3	Ubiquitylation	K535	-0.201		_RGTTVYLCEK(gl)R_
EXOSC10	Ubiquitylation	K591		-1.148	_SEVAAGVK(gl)K_
EXOSC10	Ubiquitylation	K592		-1.148	_SEVAAGVK(gl)K_
EXOSC10	Ubiquitylation	K680		-1.926	_GPLTVAQKK(gl)_
EXOSC10	Ubiquitylation	K710		-1.867	_APVSQAAK(gl)FDPSTK_
EXOSC10	Ubiquitylation	K716		-2.215	_FDPSTK(gl)IYEISNR_
EXOSC2	Ubiquitylation	K70		-0.209	_LICVK(gl)ALK_
EXOSC2	Ubiquitylation	K97		0.060	_WK(gl)VETNSR_
EXOSC2	Phosphorylation	S175	-0.346	-0.185	_LGQGVLVQVS(ph)PSLVK_
EXOSC2	Ubiquitylation	K180		-0.618	_LGQGVLVQVSPSLVK(gl)R_
EXOSC5	Ubiquitylation	K68	-1.576		_VSK(gl)EIFNK_
EXOSC5	Ubiquitylation	K92	-1.386	0.381	_IGLPGVAEK(gl)SR_
EXOSC5	Ubiquitylation	K191	-0.124		_K(gl)LLMSSTK_
EXOSC8	Ubiquitylation	K6	-0.039	-1.840	_(ac)AAGFK(gl)TVEPLEYYRR_
EXOSC8	Ubiquitylation	K19	0.825		_FLK(gl)ENCRPDGR_
EXOSC9	Ubiquitylation	K52	0.195		_ISFGTDYGCCIVELGK(gl)TR_
EXOSC9	Phosphorylation	S306	0.254	0.180	_APIDTS(ph)DVEEK_