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Query: WDR6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR6 0 -0.061 0.590 -0.760 -0.847 -0.197 -0.347

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR6 Ubiquitylation K343 0.683 _GLGVSALCFK(gl)SR_
WDR6 Phosphorylation S545 0.380 _AGAGAPVVGS(ph)GSSGGGNAFTGLGPVSTLPSLHGK_
WDR6 Ubiquitylation K855 0.268 -0.051 _MVK(gl)VDPETR_
WDR6 Ubiquitylation K708 -0.627 -0.069 _EITCVK(gl)R_
WDR6 Ubiquitylation K910 -0.462 _ILQLLAETFHHK(gl)R_

Background Information for WDR6:


Pubmed-WDR6 »
Uniprot-WDR6 »
Biogrid-WDR6 »
ProteomicsDB-WDR6 »

Tumorportal-WDR6 »
COSMIC-WDR6 »
GenomeRNAi-WDR6 »
Genecards-WDR6


Protein-protein Interactions for WDR6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARRB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC25B Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC37 Cat. description Hein, Mann, Cell 2015
Category members IP bait FTSJ1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait DMWD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Quino_amine_DH_bsu IPR011044 0


Protein complexes (CORUM database) featuring WDR6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDR6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0043560 insulin receptor substrate binding Database 0.03
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0010507 negative regulation of autophagy Database 0


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