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Query: USP9Y

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP9Y 0 0.848 0.000 -0.200 -0.309 0.196 0.205 -0.019 0.128

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP9Y Ubiquitylation K315 1.100 _SLK(gl)NLASR_
USP9Y Ubiquitylation K112 0.155 0.666 _GLDVK(gl)SEACQR_
USP9Y Ubiquitylation K2301 0.210 0.500 _IIEDCSNSEETVK(gl)LLR_
USP9Y Ubiquitylation K1045 0.212 _VLMK(gl)LMPPDSTTIEK_
USP9Y Ubiquitylation K1446 -1.104 0.061 _ELLAFQTSEKK(gl)_
USP9Y Phosphorylation S2563 -0.389 -0.274 _AQENYEGSEEVS(ph)PPQTK_
USP9Y Ubiquitylation K1445 -1.104 -0.276 _ELLAFQTSEK(gl)K_
USP9Y Ubiquitylation K1798 -1.085 _LPPVLAIQLK(gl)R_
USP9Y Ubiquitylation K1627 -1.695 _DDVFGYPQQFEDK(gl)PALSK_
USP9Y Ubiquitylation K1637 -0.957 _TEDRK(gl)EYNIGVLR_
USP9Y Ubiquitylation K2480 -0.335 _ACELCPEEVKK(gl)_

Background Information for USP9Y:


Pubmed-USP9Y »
Uniprot-USP9Y »
Biogrid-USP9Y »
ProteomicsDB-USP9Y »

Tumorportal-USP9Y »
COSMIC-USP9Y »
GenomeRNAi-USP9Y »
Genecards-USP9Y


Protein-protein Interactions for USP9Y
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSPH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HS2ST1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCKIPSD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF331 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP9Y
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Glycoside_hydrolase_SF IPR017853 0


Protein complexes (CORUM database) featuring USP9Y
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP9Y
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members Disease phenotype Partial_chromosome_Y_deletion Partial chromosome Y deletion Database 0.62
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members Disease phenotype SPERMATOGENIC_FAILURE_Y-LINKED_2 SPERMATOGENIC FAILURE Y-LINKED 2 Database 0.11
Category members GO Category GO:0070410 co-SMAD binding Database 0.03
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0


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