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Query: USP13

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP13 1 4.390 0.350 0.240
USP13 1 4.390 0.350 0.240 -1.142 0.643

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP13 Ubiquitylation K743 0.438 1.356 _DQALK(gl)ALR_
USP13 Ubiquitylation K163 0.116 1.146 _K(gl)QEVQAWDGEVR_
USP13 Ubiquitylation K478 0.243 0.990 _CLATEKVK(gl)_
USP13 Phosphorylation T623 1.685 0.623 _GTGLQPGEEELPDIAPPLVT(ph)PDEPK_
USP13 Ubiquitylation K558 0.626 0.552 _SVAVK(gl)TTR_
USP13 Ubiquitylation K418 0.291 0.339 _MFK(gl)ALIGK_
USP13 Ubiquitylation K430 0.505 0.308 _MFK(gl)AFVSK_
USP13 Ubiquitylation K470 -0.606 0.287 _IK(gl)CLATEK_
USP13 Ubiquitylation K328 0.320 0.109 _LK(gl)PMYGPGYTGLK_
USP13 Ubiquitylation K793 -0.216 0.033 _SAADSISESVPVGPK(gl)VR_
USP13 Ubiquitylation K184 -0.042 -0.044 _HAFSLK(gl)QLDNPAR_
USP13 Ubiquitylation K423 0.440 -0.090 _ALIGK(gl)GHPEFSTNR_
USP13 Ubiquitylation K435 -0.932 -0.715 _AFVSK(gl)SHPEFSSNR_
USP13 Ubiquitylation K353 1.225 _K(gl)YVDKLEK_
USP13 Ubiquitylation K357 0.847 _YVDK(gl)LEK_
USP13 Ubiquitylation K468 0.433 _FLVEEK(gl)IK_

Background Information for USP13:


Pubmed-USP13 »
Uniprot-USP13 »
Biogrid-USP13 »
ProteomicsDB-USP13 »

Tumorportal-USP13 »
COSMIC-USP13 »
GenomeRNAi-USP13 »
Genecards-USP13


Protein-protein Interactions for USP13
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPP25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCCPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members UBA/Ts_N IPR000449 0.34
Category members UBA-like IPR009060 0.17
Category members Znf_UBP IPR001607 0.05
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04


Protein complexes (CORUM database) featuring USP13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0070536 protein K63-linked deubiquitination Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0008242 omega peptidase activity Database 0.28
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0010506 regulation of autophagy Database 0
Category members GO Category GO:0030318 melanocyte differentiation Database 0


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